The Endoform Natural soft tissue  10 X 12.7 CM (4 X 5'')  is a type of restorative bioscaffold, specifically an advanced collagen wound dressing, used for the management of various acute and chronic wounds. It is derived from ovine (sheep) forestomach and provides a natural extracellular matrix (ECM) to support the body's own tissue regeneration processes. 

Key Features:

Natural Bioscaffold: Endoform Natural provides a porous ECM scaffold that helps facilitate rapid infiltration by epithelial cells and fibroblasts, supporting new tissue formation.

Composition: It retains the natural molecular structure of the ovine ECM, containing more than 150 proteins (including fibronectin, laminin, and elastin) important for wound healing.

Mechanism of Action: The dressing helps to restore the balance of proteases (enzymes) in the wound bed, moving stalled wounds into the proliferative phase of healing.

Ease of Use: When hydrated with wound exudate or sterile saline, the dry material transforms into a soft, conforming sheet that is simple for wound care professionals to apply. It can be trimmed to fit the wound size.

Integration: The bioscaffold is naturally incorporated and remodeled into the wound bed over time, so it does not need to be removed during dressing changes.

Indications for Use:

Endoform Natural is indicated for managing a wide range of wounds, including: 

Partial and full-thickness wounds

Diabetic, venous, and chronic vascular ulcers

Pressure injuries

Surgical wounds (e.g., donor sites, grafts)

Traumatic wounds (e.g., abrasions, lacerations, skin tears, first- and second-degree burns)

Tunneled/undermined wounds

Draining wounds  

Application and Duration

Preparation: The wound bed should be cleansed and debrided as necessary before application.

Application: The dry material is placed in the wound and then rehydrated.

Frequency: It can last in the wound for up to 7 days, depending on the amount of exudate; reassessment is recommended within 72 hours. A non-adherent secondary dressing is typically applied over the Endoform to manage exudate and protect the site.

Precautions: It is contraindicated for patients with a known sensitivity to ovine-derived material, third-degree burns, or wounds with an untreated clinical infection.